Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 18/20 | 1.00 |
| ▸ | GRPR | P30550 | 18/20 | 1.00 |
| ▸ | FPR1 | P21462 | 4/20 | 1.00 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.81 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397898 | 1.00 | NMBR (1.00) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL397897 | 1.00 | NMBR (1.00) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6249801 | 0.89 | NMBR (1.00) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL30901851 | 0.89 | NMBR (1.00) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6179971 | 0.89 | NMBR (1.00) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6810082 | 0.84 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6252249 | 0.84 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6252271 | 0.84 | NMBR (0.94) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6250987 | 0.83 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL7654323 | 0.83 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240173375-A1 | CHEMOTACTIC AUTOPHAGY-INHIBITING PEPTIDE, COMPOSITIONS AND METHODS RELATED THERETO | BIOTEMPT B.V. (NL) | 2024-05-30 | — | — | US | disclosed |
| CN-117836011-A | Methods and materials for combining biological agents with various chelators | 梅约医学教育与研究基金会 | 2024-04-05 | — | — | CN | disclosed |
| CN-115778961-B | Application of PD173074 in preparation of anti-itch medicament | 中国人民解放军空军军医大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-117100863-A | Use of cannabinoid systems and downstream pathways thereof for preventing and/or treating chronic itch | 南方科技大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-113512032-B | Oxadiazole thioether derivative, and preparation method and application thereof | 合肥工业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-113512032-B | Oxadiazole thioether derivative, and preparation method and application thereof | 合肥工业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-115778961-A | Application of PD173074 in preparation of anti-pruritus drugs | 中国人民解放军空军军医大学 | 2023-03-14 | — | — | CN | disclosed |