Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 12/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 11/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 10/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.45 |
| ▸ | CDK2 | P24941 | 13/20 | 0.43 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.42 |
| ▸ | CDK7 | P50613 | 7/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.42 |
| ▸ | CCNH | P51946 | 6/20 | 0.42 |
| ▸ | CCND1 | P24385 | 5/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313974 | 1.00 | CDK1 (0.45) | CDK1CDK5CCNB1CDK5R1CCNB2 | |
| SCHEMBL3242817 | 0.92 | ITGB1 (0.46) | CDK1CDK5CCNB1CDK5R1CCNB2 | |
| SCHEMBL2312171 | 0.89 | CDK2 (0.46) | CDK1CDK5CCNB1CDK5R1CCNB2 | |
| SCHEMBL2314283 | 0.83 | CDK2 (0.47) | CDK1CDK5CCNB1CDK5R1CCNB2 | |
| SCHEMBL2317564 | 0.81 | AHR (0.62) | CDK1CDK5CCNB1CDK5R1CCNB2 | |
| SCHEMBL2313988 | 0.80 | CDK2 (0.42) | CDK1CDK5CCNB1CDK5R1CCNB2 | |
| SCHEMBL21016422 | 0.80 | CDK2 (0.48) | CDK1CDK5CCNB1CDK5R1CDK2 | |
| SCHEMBL15422733 | 0.80 | CDK2 (0.42) | CDK1CDK5CCNB1CDK5R1CCNB2 | |
| SCHEMBL2315248 | 0.78 | CDK2 (0.41) | CDK1CDK5CCNB1CDK5R1CCNB2 | |
| SCHEMBL2311219 | 0.77 | CDK2 (0.46) | CDK1CDK5CCNB1CDK5R1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524604-B1 | EXPANDED HEMATOPOIETIC STEM CELLS FROM CORD BLOOD AND THEIR THERAPEUTIC USE | NOVARTIS AG (CH) | 2023-03-29 | — | — | EP | disclosed |