Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.57 |
| ▸ | CDK2 | P24941 | 3/20 | 0.57 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359403 | 1.00 | AHR (0.70) | AHRCCNE1CDK2CCNE2NPC1 | |
| SCHEMBL2318495 | 0.94 | AHR (0.61) | AHRCCNE1CDK2CCNE2NPC1 | |
| SCHEMBL2359948 | 0.92 | AHR (0.73) | AHRCCNE1CDK2CCNE2IP6K1 | |
| SCHEMBL3500316 | 0.92 | AHR (0.64) | AHRCCNE1CDK2CCNE2NPC1 | |
| SCHEMBL21016755 | 0.89 | AHR (0.58) | AHRCCNE1CDK2CCNE2SSTR1 | |
| SCHEMBL2314090 | 0.87 | AHR (0.79) | AHRCCNE1CDK2CCNE2NPC1 | |
| SCHEMBL15011335 | 0.85 | AHR (0.87) | AHRCCNE1CDK2CCNE2NPC1 | |
| SCHEMBL2313738 | 0.84 | AHR (0.71) | AHRCCNE1CDK2CCNE2NPC1 | |
| SCHEMBL21240855 | 0.83 | AHR (0.54) | AHRCCNE1CDK2CCNE2CDK9 | |
| SCHEMBL19766270 | 0.83 | AHR (0.85) | AHRCCNE1CDK2CCNE2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524604-B1 | EXPANDED HEMATOPOIETIC STEM CELLS FROM CORD BLOOD AND THEIR THERAPEUTIC USE | NOVARTIS AG (CH) | 2023-03-29 | — | — | EP | disclosed |