Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 19/20 | 0.65 |
| ▸ | KAT7 | O95251 | 1/20 | 0.42 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478 | 1.00 | CCR4 (0.65) | CCR4KAT7KAT6BKAT6AKAT5 | |
| SCHEMBL30369 | 0.94 | CCR4 (0.73) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL29434 | 0.89 | CCR4 (0.75) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30563 | 0.88 | CCR4 (0.78) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL13186541 | 0.86 | CCR4 (0.87) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL358233 | 0.86 | CCR4 (0.87) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30230 | 0.85 | CCR4 (0.71) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL31098 | 0.84 | CCR4 (0.70) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30685 | 0.84 | CCR4 (0.73) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30995 | 0.83 | CCR4 (0.77) | CCR4CCR5FFAR4SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025473-A1 | CC.CHEMOKINE RECEPTOR 4 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | WO | disclosed |