Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.69 |
| ▸ | MELK | Q14680 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24030769 | 1.00 | HDAC1 (0.69) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL29381775 | 0.85 | HDAC1 (0.73) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL24030794 | 0.85 | HDAC1 (0.73) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL24031149 | 0.85 | HDAC1 (0.60) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL24031079 | 0.84 | HDAC1 (0.81) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL24031073 | 0.82 | HDAC6 (1.00) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL24031153 | 0.82 | HDAC1 (0.77) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL24031134 | 0.80 | HDAC1 (0.75) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL24031061 | 0.80 | HDAC1 (1.00) | HDAC1HDAC6HDAC8HDAC11MELK | |
| SCHEMBL24030776 | 0.80 | HDAC1 (0.75) | HDAC1HDAC6HDAC8HDAC11MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621317-B | Inhibitors of Histone Deacetylase (HDACS) | 安基生技新药股份有限公司 | 2023-05-12 | — | — | CN | disclosed |