Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 17/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.65 |
| ▸ | MELK | Q14680 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317696 | 0.93 | HDAC6 (0.68) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317705 | 0.91 | HDAC6 (0.68) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317740 | 0.90 | HDAC6 (0.77) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317719 | 0.90 | HDAC6 (0.80) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031141 | 0.89 | HDAC6 (1.00) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317710 | 0.88 | HDAC1 (0.68) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL28357694 | 0.86 | HDAC6 (0.81) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317699 | 0.85 | HDAC6 (0.72) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317678 | 0.84 | HDAC6 (0.78) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317713 | 0.83 | HDAC1 (0.68) | HDAC6HDAC1HDAC8HDAC11MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621317-B | Inhibitors of Histone Deacetylase (HDACS) | 安基生技新药股份有限公司 | 2023-05-12 | — | — | CN | disclosed |