Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 18/20 | 1.00 |
| ▸ | CDK1 | P06493 | 18/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 18/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 18/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 16/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 16/20 | 1.00 |
| ▸ | CCNA2 | P20248 | 5/20 | 1.00 |
| ▸ | CDK2 | P24941 | 5/20 | 1.00 |
| ▸ | CCNA1 | P78396 | 5/20 | 1.00 |
| ▸ | GSK3A | P49840 | 5/20 | 0.82 |
| ▸ | CDK9 | P50750 | 3/20 | 0.69 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.69 |
| ▸ | CDC7 | O00311 | 2/20 | 0.69 |
| ▸ | PLK4 | O00444 | 2/20 | 0.69 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.69 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.69 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.69 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.69 |
| ▸ | ABL1 | P00519 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paullone 2 SCHEMBL5688525 | 1.00 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL16085135 | 0.90 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL30319771 | 0.87 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL5688272 | 0.87 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL4017123 | 0.85 | GSK3B (0.85) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL16085136 | 0.82 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| Cazpaullone SCHEMBL379127 | 0.82 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| Cazpaullone SCHEMBL29355820 | 0.82 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| Paullone SCHEMBL3178594 | 0.82 | CCNB2 (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| Paullone SCHEMBL29407267 | 0.82 | CCNB2 (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115969814-A | Novel pharmaceutical formulations containing indirubin and derivatives thereof and methods of making and using the same | 法斯瑞斯公司 | 2023-04-18 | — | — | CN | disclosed |