Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 1.00 |
| ▸ | CDK1 | P06493 | 15/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 14/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 14/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 14/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 7/20 | 0.50 |
| ▸ | GSK3A | P49840 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | CDK9 | P50750 | 2/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5688608 | 1.00 | GSK3B (1.00) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL5690667 | 0.88 | GSK3B (0.78) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL30319775 | 0.88 | GSK3B (0.78) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL15264706 | 0.87 | GSK3B (0.77) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL6012263 | 0.86 | GSK3B (1.00) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL30319745 | 0.84 | GSK3B (1.00) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL5688439 | 0.84 | GSK3B (1.00) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL5801923 | 0.83 | CDK1 (0.79) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL30319836 | 0.80 | GSK3B (1.00) | GSK3BCDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL5688624 | 0.80 | GSK3B (1.00) | GSK3BCDK1CCNB2CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115969814-A | Novel pharmaceutical formulations containing indirubin and derivatives thereof and methods of making and using the same | 法斯瑞斯公司 | 2023-04-18 | — | — | CN | disclosed |