SCHEMBL30320243

SCHEMBL30320243

c1ccc2cc(-n3c4ccccc4c4ccccc43)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.56
ATM Q13315 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HSP90AA1 P07900 1/20 0.46
ALDH1A1 P00352 3/20 0.45
RAB9A P51151 2/20 0.45
PMM2 O15305 1/20 0.45
MPI P34949 1/20 0.45
PHOSPHO1 Q8TCT1 1/20 0.45
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTR3A P46098 2/20 0.43
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR5A P47898 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
BACE1 P56817 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL274318 1.00 KDM4E (0.56) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL13956890 0.96 KDM4E (0.60) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL10450016 0.94 KDM4E (0.50) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL16409623 0.94 KDM4E (0.50) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL21671315 0.94 KDM4E (0.50) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL6938289 0.94 KDM4E (0.50) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL16409588 0.94 KDM4E (0.50) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL21671366 0.94 KDM4E (0.50) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL16917379 0.94 KDM4E (0.54) KDM4EATML3MBTL1HSP90AA1ALDH1A1
SCHEMBL13828934 0.93 KDM4E (0.48) KDM4EATML3MBTL1HSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117776830-A Full deuteration preparation method of polycyclic aromatic hydrocarbon 宁波萃英化学技术有限公司 2024-03-29 CN claimed
CN-117776830-A Full deuteration preparation method of polycyclic aromatic hydrocarbon 宁波萃英化学技术有限公司 2024-03-29 CN disclosed
CN-115974764-A Hole transport material and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2023-04-18 CN disclosed
CN-113004262-B Organic material and application thereof 北京云基科技股份有限公司 2023-02-17 CN disclosed