Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.58 |
| ▸ | SRC | P12931 | 7/20 | 0.57 |
| ▸ | KDR | P35968 | 6/20 | 0.57 |
| ▸ | EGFR | P00533 | 5/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.57 |
| ▸ | ABL1 | P00519 | 4/20 | 0.57 |
| ▸ | HCK | P08631 | 4/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.57 |
| ▸ | MTOR | P42345 | 4/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.57 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.57 |
| ▸ | PRKDC | P78527 | 4/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.57 |
| ▸ | RET | P07949 | 2/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25793050 | 1.00 | BTK (0.58) | BTKSRCKDREGFRPIK3CD | |
| SCHEMBL15706055 | 0.94 | BTK (0.58) | BTKSRCKDREGFRPIK3CD | |
| SCHEMBL17106337 | 0.88 | BTK (0.57) | BTKSRCKDREGFRPIK3CD | |
| SCHEMBL15706054 | 0.85 | BTK (0.61) | BTKSRCKDREGFRPIK3CD | |
| SCHEMBL5801348 | 0.85 | ABL1 (0.57) | SRCKDREGFRPIK3CDABL1 | |
| SCHEMBL4820128 | 0.83 | SRC (0.62) | BTKSRCKDREGFRPIK3CD | |
| SCHEMBL24197244 | 0.83 | BTK (0.59) | BTKSRCKDREGFRPIK3CD | |
| SCHEMBL24096567 | 0.83 | SRC (0.61) | SRCKDREGFRPIK3CDABL1 | |
| SCHEMBL1321013 | 0.83 | BTK (0.57) | BTKSRCKDREGFRPIK3CD | |
| SCHEMBL1318797 | 0.83 | BTK (0.57) | BTKSRCKDREGFRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161933-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |