Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK7 | Q8TDX7 | 11/20 | 0.61 |
| ▸ | FLT3 | P36888 | 8/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096917 | 1.00 | NEK7 (0.61) | NEK7FLT3RIPK1 | |
| SCHEMBL25821747 | 0.93 | NEK7 (0.61) | NEK7FLT3RIPK1 | |
| SCHEMBL30320657 | 0.89 | NEK7 (0.62) | NEK7FLT3RIPK1 | |
| SCHEMBL24096475 | 0.89 | NEK7 (0.62) | NEK7FLT3RIPK1 | |
| SCHEMBL30320543 | 0.89 | NEK7 (0.65) | NEK7 | |
| SCHEMBL24096598 | 0.89 | NEK7 (0.65) | NEK7 | |
| SCHEMBL24096477 | 0.88 | NEK7 (0.64) | NEK7FLT3RIPK1 | |
| SCHEMBL30320555 | 0.88 | NEK7 (0.64) | NEK7FLT3RIPK1 | |
| SCHEMBL24096525 | 0.88 | NEK7 (0.66) | NEK7FLT3RIPK1 | |
| SCHEMBL30320515 | 0.88 | NEK7 (0.66) | NEK7FLT3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161933-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |