⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696931 | 1.00 | — | — | |
| SCHEMBL1230178 | 0.79 | — | — | |
| SCHEMBL29760935 | 0.79 | — | — | |
| SCHEMBL30227809 | 0.77 | — | — | |
| SCHEMBL7216955 | 0.77 | — | — | |
| SCHEMBL5728823 | 0.77 | — | — | |
| SCHEMBL2008664 | 0.77 | — | — | |
| SCHEMBL681074 | 0.77 | — | — | |
| SCHEMBL31288450 | 0.77 | — | — | |
| SCHEMBL9383289 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642782-A2 | ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF | Pliant Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| CN-119528915-A | Compounds for inhibiting apoptosis and methods of making the same | 中国科学院上海有机化学研究所 | 2025-02-28 | — | — | CN | disclosed |
| CN-115806557-B | Compounds for inhibiting apoptosis and methods of making the same | 中国科学院上海有机化学研究所 | 2025-02-14 | — | — | CN | disclosed |
| CN-117794898-A | 3-pyrrolylsulfonamide compounds as GPR17 antagonists | 瑞文德医疗公众有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115806557-A | Compound for inhibiting programmed cell death and preparation method thereof | 中国科学院上海有机化学研究所 | 2023-03-17 | — | — | CN | disclosed |