⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581046 | 0.67 | — | — | |
| SCHEMBL49945 | 0.61 | — | — | |
| SCHEMBL276631 | 0.61 | — | — | |
| Phosphine SCHEMBL9007695 | 0.55 | — | — | |
| SCHEMBL18920332 | 0.55 | — | — | |
| Ethane SCHEMBL6550234 | 0.55 | — | — | |
| Hydrochloric Acid SCHEMBL641352 | 0.55 | — | — | |
| SCHEMBL18919813 | 0.55 | — | — | |
| SCHEMBL21404302 | 0.55 | — | — | |
| SCHEMBL9227174 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | claimed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | claimed |
| US-20220220096-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-07-14 | — | — | US | claimed |
| EP-3956322-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-02-23 | — | — | EP | claimed |
| CN-113710664-A | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2021-11-26 | — | — | CN | claimed |
| WO-2020211839-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2020-10-22 | — | — | WO | claimed |
| US-5686386-A | OF A SYNERGISTIC AMOUNT OF AN ORGANOPHOSPHOROUS COMPOUND AND A 3-SUBSTITUTED PHENYLPYRAZOLE DERIVATIVE | NIHON NOHYAKU CO., LTD. (JP) | 1997-11-11 | — | — | US | claimed |
| EP-0257296-B1 | 4-CYANO(NITRO)-5-OXY(THIO)-PYRAZOLE DERIVATIVES | BAYER AG (DE) | 1993-05-12 | — | — | EP | claimed |
| US-4770692-A | 4-cyano(nitro)-5-oxy(thio)-pyrazole derivatives, composition containing them, and herbicidal and plant growth regulating methods of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | claimed |
| EP-0257296-A1 | 4-Cyano(nitro)-5-oxy(thio)-pyrazole derivatives | BAYER AG (DE) | 1988-03-02 | — | — | EP | claimed |
| EP-0009022-B1 | PROCESSES FOR PREPARING D,L-2-AMINO-4((HYDROXY)(METHYL)PHOSPHINOYL)-BUTYRIC ACID AND AN ACETAL OF AN ESTER OF 3-OXOPROPYLMETHYL PHOSPHINIC ACID | MEIJI SEIKA KAISHA LTD. (JP) | 1982-07-07 | — | — | EP | claimed |
| US-3978078-A | Process for the preparation of ampicillin | RHONE-POULENC S.A. (FR) | 1976-08-31 | — | — | US | claimed |
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116348464-A | Benzimidazolone GLP-1 receptor agonists and uses thereof | 杭州中美华东制药有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20220220096-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| US-4770692-A | 4-cyano(nitro)-5-oxy(thio)-pyrazole derivatives, composition containing them, and herbicidal and plant growth regulating methods of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
| EP-0257296-A1 | 4-Cyano(nitro)-5-oxy(thio)-pyrazole derivatives | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0009022-B1 | PROCESSES FOR PREPARING D,L-2-AMINO-4((HYDROXY)(METHYL)PHOSPHINOYL)-BUTYRIC ACID AND AN ACETAL OF AN ESTER OF 3-OXOPROPYLMETHYL PHOSPHINIC ACID | MEIJI SEIKA KAISHA LTD. (JP) | 1982-07-07 | — | — | EP | disclosed |
| US-3978078-A | Process for the preparation of ampicillin | RHONE-POULENC S.A. (FR) | 1976-08-31 | — | — | US | disclosed |