SCHEMBL30322467

SCHEMBL30322467

CCCOCC1(COCCC)c2ccccc2-c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 8/20 0.40
APEX1 P27695 1/20 0.38
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
CNR2 P34972 1/20 0.35
PGR P06401 2/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20995933 1.00 PDK2 (0.40) PDK2APEX1MEN1KMT2ACYP2C9
SCHEMBL15355422 0.96 PDK2 (0.38) PDK2APEX1MEN1KMT2ACYP2C9
SCHEMBL27663058 0.90 PDK2 (0.40) PDK2APEX1MEN1KMT2ACYP2C9
SCHEMBL20995914 0.89 PDK2 (0.44) PDK2APEX1MEN1KMT2ACYP2C9
SCHEMBL30322706 0.89 PDK2 (0.44) PDK2APEX1MEN1KMT2ACYP2C9
SCHEMBL5084607 0.89 PDK2 (0.35) PDK2APEX1MEN1KMT2ACYP2C9
SCHEMBL5080886 0.87 PDK2 (0.34) PDK2APEX1KMT2ACYP2C19CNR2
SCHEMBL5081777 0.86 PDK2 (0.33) PDK2APEX1MEN1KMT2ACYP2C9
SCHEMBL27861863 0.85 CYP2C9 (0.35) PDK2APEX1MEN1KMT2ACYP2C9
SCHEMBL5085242 0.85 PDK2 (0.33) PDK2APEX1MEN1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057913-B Solid catalyst component for olefin polymerization 住友化学株式会社 2024-10-11 CN disclosed
CN-113105690-B Heterophasic propylene polymer material and use thereof 住友化学株式会社 2024-03-01 CN disclosed
CN-111836855-B Heterophasic propylene polymer material 住友化学株式会社 2023-09-22 CN disclosed
CN-115926028-A Process for producing solid catalyst component for olefin polymerization, process for producing catalyst for olefin polymerization, and process for producing olefin polymer 住友化学株式会社 2023-04-07 CN disclosed
CN-110382574-B Heterophasic propylene polymer material and propylene resin composition 住友化学株式会社 2023-03-31 CN disclosed