Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807107 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29388103 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL8741038 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL2226707 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL5945948 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7615094 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL12282726 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL25015227 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Moxifloxacin SCHEMBL24007 | 0.70 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Moxifloxacin SCHEMBL12156451 | 0.70 | KDM4E (0.98) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4164626-A1 | COMBINATION ANTIBACTERIAL COMPOSITION AND METHOD FOR ANTIBACTERIAL THERAPY | Mylan Laboratories Ltd. (IN) | 2023-04-19 | — | — | EP | disclosed |
| EP-4164645-A1 | COMBINATION ANTIBACTERIAL COMPOSITION AND METHOD FOR ANTIBACTERIAL THERAPY | The Global Alliance for TB Drug Development, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |