Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 7/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.33 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | TEC | P42680 | 2/20 | 0.32 |
| ▸ | TXK | P42681 | 2/20 | 0.32 |
| ▸ | BMX | P51813 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30325959 | 0.95 | BTK (0.34) | PIK3CDBTKEGFRCSNK2A2CSNK2A1 | |
| SCHEMBL30326048 | 0.93 | BTK (0.37) | PIK3CDBTKEGFRCSNK2A2CSNK2A1 | |
| SCHEMBL30325702 | 0.90 | BTK (0.36) | BTKEGFRCSNK2A2CSNK2A1MCHR1 | |
| SCHEMBL30326063 | 0.89 | BTK (0.34) | BTKEGFRCSNK2A2CSNK2A1MCHR1 | |
| SCHEMBL30325951 | 0.87 | CSNK2A2 (0.47) | BTKCSNK2A2CSNK2A1MCHR1TNK2 | |
| SCHEMBL30325631 | 0.86 | TNK2 (0.35) | BTKEGFRCSNK2A2CSNK2A1EIF2S1 | |
| SCHEMBL30325666 | 0.85 | TNK2 (0.36) | BTKEGFRCSNK2A2CSNK2A1EIF2S1 | |
| SCHEMBL30326043 | 0.85 | CSNK2A2 (0.34) | BTKEGFRCSNK2A2CSNK2A1EIF2S1 | |
| SCHEMBL30326023 | 0.85 | BTK (0.35) | BTKEGFRCSNK2A2CSNK2A1EIF2AK3 | |
| SCHEMBL30325957 | 0.85 | FGFR1 (0.41) | PIK3CDBTKEGFRCSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383905-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2024-11-21 | — | — | US | claimed |
| EP-4405358-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H Pharmaceuticals Co., Ltd. (CN) | 2024-07-31 | — | — | EP | claimed |
| WO-2023046117-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2023-03-30 | — | — | WO | claimed |
| US-20240383905-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| EP-4405358-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H Pharmaceuticals Co., Ltd. (CN) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023046117-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2023-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383905-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | FGFR1, FGFR3, FGFR4 | PIK3CD 889/4885BTK 168/4885EGFR 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.