Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17101527 | 0.83 | DDB1 (0.45) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL21413281 | 0.81 | DDB1 (0.43) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL23145355 | 0.80 | USP2 (0.45) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL25291221 | 0.79 | DDB1 (0.43) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL31066539 | 0.77 | USP2 (0.45) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL30327935 | 0.77 | DDB1 (0.39) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL8217780 | 0.76 | USP2 (0.50) | USP2SMN1; SMN2GPR119NAMPTHPGD | |
| SCHEMBL16984146 | 0.76 | USP2 (0.50) | USP2SMN1; SMN2GPR119NAMPTHPGD | |
| SCHEMBL23138781 | 0.76 | USP2 (0.44) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL23138782 | 0.76 | USP2 (0.44) | DDB1CRBNKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |