SCHEMBL3033008

SCHEMBL3033008

C[C](C)CC(=O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.73
MEN1 O00255 2/20 0.73
CYP3A4 P08684 2/20 0.73
HPGD P15428 2/20 0.73
MAPK1 P28482 2/20 0.73
MAPT P10636 2/20 0.73
TDP1 Q9NUW8 2/20 0.73
ALOX15 P16050 2/20 0.73
CES1 P23141 2/20 0.73
KDM4E B2RXH2 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
NPC1 O15118 2/20 0.63
RAB9A P51151 2/20 0.63
PTPN1 P18031 2/20 0.61
ERCC5 P28715 1/20 0.61
FEN1 P39748 1/20 0.61
ALDH1A1 P00352 2/20 0.57
HIF1A Q16665 2/20 0.57
PLOD2 O00469 2/20 0.57
PLOD3 O60568 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzoylmethane SCHEMBL28139772 0.88 KMT2A (0.85) KMT2AMEN1CYP3A4HPGDMAPK1
SCHEMBL29110128 0.86 KMT2A (0.73) KMT2AMEN1CYP3A4HPGDMAPK1
Hydrogen Peroxide SCHEMBL28455182 0.86 KMT2A (0.73) KMT2AMEN1CYP3A4HPGDMAPK1
SCHEMBL15116 0.86 KMT2A (0.73) KMT2AMEN1CYP3A4HPGDMAPK1
SCHEMBL11373627 0.86 KMT2A (0.73) KMT2AMEN1CYP3A4HPGDMAPK1
SCHEMBL29110144 0.86 KMT2A (0.73) KMT2AMEN1CYP3A4HPGDMAPK1
Benzene SCHEMBL8209405 0.86 KMT2A (0.73) KMT2AMEN1CYP3A4HPGDMAPK1
Dibenzoylmethane SCHEMBL10356288 0.85 MEN1 (1.00) KMT2AMEN1CYP3A4HPGDMAPK1
Dibenzoylmethane SCHEMBL39582 0.85 MEN1 (1.00) KMT2AMEN1CYP3A4HPGDMAPK1
Dibenzoylmethane SCHEMBL1704711 0.85 MEN1 (1.00) KMT2AMEN1CYP3A4HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113272021-A Water-in-oil type emulsion cosmetic for sunscreen 花王株式会社 2021-08-17 CN disclosed
CN-110229428-A A kind of High heat conductivity nanocomposite rubber and preparation method thereof 王军军 2019-09-13 CN disclosed
CN-109796855-A A kind of insulating moulding coating and preparation method for automobile case 成都其其小数科技有限公司 2019-05-24 CN disclosed
CN-105085309-B A kind of preparation method and application of polymerisable monomer 中国石油化工股份有限公司 2017-11-07 CN disclosed
CN-105085304-B A kind of preparation method and application of polymerisable monomer 中国石油化工股份有限公司 2017-06-30 CN disclosed
CN-106751348-A Aircraft arrestment bed is blocked and stops unit top cover and preparation method thereof 周志亮 2017-05-31 CN disclosed
CN-105440167-B Macromolecular photoinitiator containing diphenyl ketone groups and preparation method of macromolecular photoinitiator 中山大学 2017-04-19 CN disclosed
CN-105085305-B A kind of preparation method and application of polymerisable monomer 中国石油化工股份有限公司 2017-03-29 CN disclosed
CN-105085306-B Preparation method and application of polymerizable monomer 中国石油化工股份有限公司 2017-02-15 CN disclosed
CN-102532162-B 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMA CO LTD 2015-05-27 CN disclosed
US-5071856-A CARBOSTYRIL DERIVATIVES AND SALTS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-12-10 US disclosed
US-5053514-A Side effect reduction; carbostyril derivatives OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1991-10-01 US disclosed
CN-1046529-A Carbostyril derivative OTSUKA PHARMA CO LTD (JP) 1990-10-31 CN disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
EP-0355652-A2 Polymers of substituted (2-haloalkoxy-1,1,2 trifluoroethoxy)styrene, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-28 EP disclosed
EP-0355583-A2 Cardiotonics OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-02-28 EP disclosed
US-4886809-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-12-12 US disclosed
EP-0290385-A1 Process for preparing 4-acyloxy-3-hydroxyethyl-azetidinones CIBA-GEIGY AG (CH) 1988-11-09 EP disclosed
EP-0236140-A2 Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-09-09 EP disclosed
US-4657975-A MOLDABLE BLEND OF POLYMER OF UNSATURATED ANHYDRIDE AND AROMATIC VINYL COMPOUND AND POLYMER OF AN UNSATURATED EPOXIDE; IMPACT STRENGTH SUMITOMO NAUGATUCK CO., LTD. (JP) 1987-04-14 US disclosed