Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | POLA1 | P09884 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190487 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL12192678 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL6415465 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL16046101 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL20637044 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL40101 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL7112187 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL3621835 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL19816815 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB | |
| SCHEMBL15689621 | 1.00 | MAPT (0.59) | MAPTKMT2ATSHRDGKAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10478464-B2 | Compositions and methods of use | Shah, Kirit (US) | 2019-11-19 | — | — | US | disclosed |
| EP-2381950-B1 | hydroxyhexadecanoic acid for the treatment of cancer | VANAS ONCOLOGY (US) | 2013-11-13 | — | — | EP | disclosed |
| EP-2381950-B1 | hydroxyhexadecanoic acid for the treatment of cancer | VANAS ONCOLOGY (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20100209543-A1 | COMPOSITIONS AND METHODS OF USE | VANAS ONCOLOGY (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100209543-A1 | COMPOSITIONS AND METHODS OF USE | VANAS ONCOLOGY (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100209543-A1 | COMPOSITIONS AND METHODS OF USE | VANAS ONCOLOGY (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010083311-A2 | COMPOSITIONS AND METHODS OF USE | VANAS ONCOLOGY (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209543-A1 | COMPOSITIONS AND METHODS OF USE | MKI67, VHL, CCNC | MAPT 616/4885KMT2A 2157/4885TSHR 4443/4885 |
| US-10478464-B2 | Compositions and methods of use | MKI67, VHL, CCNC | MAPT 616/4885KMT2A 2157/4885TSHR 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.