SCHEMBL30335258

SCHEMBL30335258

COc1ccc2c(c1)OC(c1ccc(O)c(O)c1)CC2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 13/20 1.00
MAOB P27338 8/20 0.77
CYP3A4 P08684 1/20 0.77
PTPN1 P18031 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371778 0.88 CYP19A1 (1.00) CYP19A1MAOBCYP3A4
SCHEMBL28690004 0.88 CYP19A1 (1.00) CYP19A1MAOBCYP3A4
Liquiritigenin Dimethyl Ether SCHEMBL3303937 0.87 CYP19A1 (1.00) CYP19A1MAOBCYP3A4
Liquiritigenin Dimethyl Ether SCHEMBL13394438 0.87 CYP19A1 (1.00) CYP19A1MAOBCYP3A4
SCHEMBL7030024 0.84 CYP19A1 (0.80) CYP19A1MAOBCYP3A4PTPN1
SCHEMBL13394439 0.84 MAOB (1.00) CYP19A1MAOBCYP3A4
Butin SCHEMBL68554 0.83 CYP19A1 (1.00) CYP19A1MAOBCYP3A4PTPN1
SCHEMBL1895399 0.83 MAOB (1.00) CYP19A1MAOBCYP3A4
Butin SCHEMBL29929348 0.83 CYP19A1 (1.00) CYP19A1MAOBCYP3A4PTPN1
Butin SCHEMBL29929512 0.83 CYP19A1 (1.00) CYP19A1MAOBCYP3A4PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO disclosed