SCHEMBL3033593

SCHEMBL3033593

c1cc(-c2ccc3ncc(-c4ccncc4)n3n2)ccn1

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FYN P06241 20/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18613433 0.94 FYN (1.00) FYN
SCHEMBL18613682 0.94 FYN (1.00) FYN
SCHEMBL18613662 0.89 FYN (1.00) FYN
SCHEMBL21672306 0.87 FYN (0.69) FYN
SCHEMBL20485717 0.87 FYN (1.00) FYN
SCHEMBL21672450 0.85 FYN (0.67) FYN
SCHEMBL18613381 0.85 FYN (1.00) FYN
SCHEMBL18613807 0.85 FYN (1.00) FYN
SCHEMBL18613362 0.84 FYN (1.00) FYN
SCHEMBL20485758 0.84 FYN (0.73) FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100216798-A1 FUSED HETEROCYCLES AS LCK INHIBITORS ASTELLAS PHARMA INC (JP) 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100216798-A1 FUSED HETEROCYCLES AS LCK INHIBITORS LCK, ZAP70, FYN FYN 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.