Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12832973 | 1.00 | MAPT (0.57) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29177222 | 0.90 | SMPD3 (0.50) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20124827 | 0.84 | HRH3 (0.54) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12875446 | 0.83 | GRIN2D (0.47) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3665634 | 0.83 | PTPN11 (0.48) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19998348 | 0.83 | GRIN2D (0.59) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29499599 | 0.83 | GRIN2D (0.59) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25567554 | 0.83 | GRIN2D (0.43) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL853768 | 0.83 | GRIN2D (0.49) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25195031 | 0.82 | GRIN2D (0.46) | MAPTGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |