Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | EDNRB | P24530 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23886840 | 1.00 | S1PR3 (0.39) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL30176297 | 1.00 | S1PR3 (0.39) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL30176318 | 0.91 | S1PR3 (0.41) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL23886953 | 0.91 | S1PR3 (0.41) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL23898572 | 0.90 | S1PR3 (0.40) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL23886655 | 0.89 | S1PR3 (0.38) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL30337964 | 0.89 | S1PR3 (0.38) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL30176369 | 0.89 | S1PR3 (0.38) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL30176268 | 0.88 | EDNRB (0.39) | S1PR3EDNRBEDNRAHTR3AS1PR1 | |
| SCHEMBL26603170 | 0.88 | EDNRB (0.39) | S1PR3EDNRBEDNRAHTR3AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916749-A | Substituted 5-hydroxyindole compounds as alpha-1 antitrypsin modulators | 弗特克斯药品有限公司 | 2023-04-04 | — | — | CN | disclosed |