Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23886885 | 1.00 | SCN9A (0.47) | SCN9AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL23898506 | 0.93 | NPC1 (0.46) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL23898665 | 0.92 | MEN1 (0.42) | SCN9AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL23898368 | 0.90 | KMT2A (0.41) | SCN9AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL30176364 | 0.88 | MEN1 (0.43) | SCN9AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL23886827 | 0.88 | MEN1 (0.43) | SCN9AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL23898666 | 0.88 | MEN1 (0.39) | SCN9AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL23898552 | 0.82 | NPC1 (0.42) | MEN1NPC1RAB9AKMT2ASRD5A2 | |
| SCHEMBL23883696 | 0.81 | SCN9A (0.40) | SCN9ARORCCNR1CNR2MAOA | |
| SCHEMBL23883622 | 0.81 | SCN9A (0.43) | SCN9ARORCCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916749-A | Substituted 5-hydroxyindole compounds as alpha-1 antitrypsin modulators | 弗特克斯药品有限公司 | 2023-04-04 | — | — | CN | disclosed |