⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109649 | 1.00 | — | — | |
| SCHEMBL3923465 | 1.00 | — | — | |
| SCHEMBL1195610 | 1.00 | — | — | |
| SCHEMBL41401 | 0.94 | — | — | |
| SCHEMBL5409330 | 0.94 | — | — | |
| SCHEMBL23495442 | 0.89 | — | — | |
| SCHEMBL1985723 | 0.89 | — | — | |
| Bromide SCHEMBL6722331 | 0.89 | — | — | |
| Phosphine SCHEMBL22589046 | 0.89 | — | — | |
| SCHEMBL11677028 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638010-B1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE DERIVATIVES STARTING FROM N-(2,2-DIFLUOROETHYL)PROP-2-EN-1-AMINE | BAYER IP GMBH (DE) | 2014-12-31 | — | — | EP | claimed |
| EP-2638001-B1 | METHOD FOR PRODUCING 2,2-DIFLUOROETHYLAMINE BASED ON PROP-2-EN-1-AMINE | BAYER IP GMBH (DE) | 2014-07-02 | — | — | EP | claimed |
| US-8766012-B2 | Process for the preparation of 2,2-difluoroethylamine starting from prop-2-en-1-amine | BAYER CROPSCIENCE AG (DE) | 2014-07-01 | — | — | US | claimed |
| US-8586756-B2 | Process for the preparation of 2,2-difluoroethylamine derivatives starting from N-(2,2-difluoroethyl)prop-2-en-1-amine | BAYER CROPSCIENCE AG (DE) | 2013-11-19 | — | — | US | claimed |
| US-20120142971-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM PROP-2-EN-1-AMINE | BAYER CROPSCIENCE AG (DE) | 2012-06-07 | — | — | US | claimed |
| US-20120123130-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE DERIVATIVES STARTING FROM N-(2,2-DIFLUOROETHYL)PROP-2-EN-1-AMINE | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | claimed |
| US-20100204463-A1 | Preparation Of Synthetic Nucleosides via Pi-Allyl Transition Metal Complex Formation | EMORY UNIVERSITY | 2010-08-12 | — | — | US | claimed |
| EP-2185508-A1 | PREPARATION OF SYNTHETIC NUCLEOSIDES VIA pi-ALLYL TRANSITION METAL COMPLEX FORMATION | Emory University (US) | 2010-05-19 | — | — | EP | claimed |
| WO-2009021114-A1 | PREPARATION OF SYNTHETIC NUCLEOSIDES VIA π-ALLYL TRANSITION METAL COMPLEX FORMATION | EMORY UNIVERSITY (US) | 2009-02-12 | — | — | WO | claimed |
| US-4101566-A | Oxidative addition production of trans-halo-2(1,3-alkadienyl)bis(triethylphosphine) complexes of nickel(II), palladium(II), and platinum(II) | PHILLIPS PETROLEUM COMPANY (US) | 1978-07-18 | — | — | US | claimed |
| JP-55087728-A | — | — | None | — | — | JP | disclosed |
| CN-110204558-B | Synthesis of cephalosporin compounds | 默沙东公司 | 2022-05-06 | — | — | CN | disclosed |
| US-11059835-B2 | Synthesis of cephalosporin compounds | MERCK SHARP & DOHME CORP. (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200385404-A1 | SYNTHESIS OF CEPHALOSPORIN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2020-12-10 | — | — | US | disclosed |
| EP-2638010-B1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE DERIVATIVES STARTING FROM N-(2,2-DIFLUOROETHYL)PROP-2-EN-1-AMINE | BAYER IP GMBH (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20100087643-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE | KANEKA CORPORATION (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-2119709-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE | Kaneka Corporation (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2009021114-A1 | PREPARATION OF SYNTHETIC NUCLEOSIDES VIA π-ALLYL TRANSITION METAL COMPLEX FORMATION | EMORY UNIVERSITY (US) | 2009-02-12 | — | — | WO | disclosed |
| US-4230719-A | Novel 2-[4-(3-methyl-2-thienyl)phenyl]propionic acid and pharmaceutically acceptable salt thereof and method for treating symptoms of inflammation and pain | TOYAMA CHEMICAL CO., LTD. (JP) | 1980-10-28 | — | — | US | disclosed |
| JP-S5587728-A | PREPARATION OF 5-ALKENYLNORBORNENE-2 | MITSUBISHI PETROCHEM CO LTD | 1980-07-02 | — | — | JP | disclosed |