Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.58 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994490 | 1.00 | COMT (0.58) | COMTHPSEPLAUMAPK14PRSS12 | |
| SCHEMBL14381770 | 0.89 | COMT (0.66) | COMTHPSEPLAUPRSS12MMP2 | |
| SCHEMBL8769684 | 0.88 | COMT (0.70) | COMTHPSEPRSS12MMP2MMP9 | |
| SCHEMBL8770496 | 0.85 | HPSE (0.61) | HPSEPRSS12MMP2MMP9MMP8 | |
| SCHEMBL14381555 | 0.85 | COMT (0.70) | COMTHPSEPRSS12MMP2MMP9 | |
| SCHEMBL14381860 | 0.85 | COMT (0.70) | COMTHPSEPRSS12MMP2MMP9 | |
| SCHEMBL14381881 | 0.85 | COMT (0.70) | COMTHPSEPRSS12MMP2MMP9 | |
| SCHEMBL14381528 | 0.84 | COMT (0.60) | COMTHPSEPLAUPRSS12MMP2 | |
| SCHEMBL14381920 | 0.84 | COMT (0.60) | COMTHPSEPLAUPRSS12MMP2 | |
| SCHEMBL14381916 | 0.84 | COMT (0.60) | COMTHPSEPLAUPRSS12MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234640-B | Benzimidazole derivatives as anticancer agents | 利昂贝拉尔中心 | 2023-04-07 | — | — | CN | disclosed |