Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344911 | 0.91 | CHRNB4 (0.47) | FAAHCHRNB2CHRNB4CHRNA3CHRNB1 | |
| SCHEMBL25155906 | 0.91 | CHRNB4 (0.47) | FAAHCHRNB2CHRNB4CHRNA3CHRNB1 | |
| SCHEMBL30343995 | 0.90 | KDM1A (0.41) | FAAHNR1D1 | |
| SCHEMBL25156235 | 0.90 | KDM1A (0.41) | FAAHNR1D1 | |
| SCHEMBL30344757 | 0.89 | PREP (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30344206 | 0.89 | CHRNB4 (0.44) | CHRNB2CHRNB4CHRNA3CHRNB1CHRNB3 | |
| SCHEMBL25155195 | 0.89 | CHRNB4 (0.44) | CHRNB2CHRNB4CHRNA3CHRNB1CHRNB3 | |
| SCHEMBL25155307 | 0.88 | KDM1A (0.44) | HCRTR1HCRTR2NR1D1 | |
| SCHEMBL30344795 | 0.88 | KDM1A (0.44) | HCRTR1HCRTR2NR1D1 | |
| SCHEMBL25156314 | 0.88 | CHRNB4 (0.44) | CHRNB2CHRNB4CHRNA3CHRNB1CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |