SCHEMBL30345321

SCHEMBL30345321

Fc1cc(-c2csc(OC3CCC3)n2)cc(F)c1OCC1CC1

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 19/20 0.70
NR4A2 P43354 1/20 0.33
DHODH Q02127 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17882719 0.82 FFAR4 (1.00) FFAR4
SCHEMBL17882593 0.81 FFAR4 (0.68) FFAR4
SCHEMBL15580577 0.81 FFAR4 (0.49) FFAR4
SCHEMBL474265 0.80 FFAR4 (0.46) FFAR4
SCHEMBL19687551 0.78 FFAR4 (0.64) FFAR4NR4A2DHODH
SCHEMBL30345252 0.77 FFAR4 (0.53) FFAR4
SCHEMBL30345332 0.77 FFAR4 (0.60) FFAR4
SCHEMBL29582829 0.76 FFAR4 (0.72) FFAR4
SCHEMBL17882569 0.75 FFAR4 (0.60) FFAR4
SCHEMBL17882628 0.75 FFAR4 (0.64) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3239143-B1 BIARYL DERIVATIVE AS GPR120 AGONIST LG CHEMICAL LTD (KR) 2023-03-22 EP claimed