SCHEMBL30346014

SCHEMBL30346014

CCCC(=O)On1c(CCC)nc2c(N)nc3ccccc3c21

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.57
TLR8 Q9NR97 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2706349 0.83 TLR7 (0.65) TLR7TLR8
SCHEMBL2706417 0.83 TLR7 (0.59) TLR7TLR8
SCHEMBL2708969 0.82 TLR7 (0.63) TLR7TLR8
SCHEMBL2707168 0.81 TLR7 (0.62) TLR7TLR8
SCHEMBL2706574 0.80 TLR7 (0.66) TLR7TLR8
SCHEMBL4155419 0.79 TLR7 (0.62) TLR7TLR8
SCHEMBL2707603 0.78 TLR7 (0.67) TLR7TLR8
SCHEMBL5617210 0.78 TLR7 (0.71) TLR7TLR8
SCHEMBL4540366 0.78 TLR7 (0.67) TLR7TLR8
SCHEMBL5617065 0.77 TLR7 (0.69) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4419112-A1 IMMUNOTHERAPIES FOR THE TREATMENT OF CANCER Ohio State Innovation Foundation (US) 2024-08-28 EP disclosed
WO-2023070132-A1 IMMUNOTHERAPIES FOR THE TREATMENT OF CANCER OHIO STATE INNOVATION FOUNDATION (US) 2023-04-27 WO disclosed