Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 7/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.35 |
| ▸ | CDK2 | P24941 | 7/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.35 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522659 | 1.00 | DYRK1A (0.38) | DYRK1ACLK2CLK3MAP3K11BRD4 | |
| SCHEMBL30347891 | 0.89 | MAP3K11 (0.44) | DYRK1ACLK2CLK3MAP3K11DYRK1B | |
| SCHEMBL25522650 | 0.89 | MAP3K11 (0.44) | DYRK1ACLK2CLK3MAP3K11DYRK1B | |
| SCHEMBL30348361 | 0.89 | DYRK1A (0.38) | DYRK1ACLK2CLK3MAP3K11BRD4 | |
| SCHEMBL25522539 | 0.89 | DYRK1A (0.38) | DYRK1ACLK2CLK3MAP3K11BRD4 | |
| SCHEMBL25522655 | 0.87 | MAP3K11 (0.41) | DYRK1ACLK2CLK3MAP3K11BRD4 | |
| SCHEMBL30347890 | 0.87 | MAP3K11 (0.41) | DYRK1ACLK2CLK3MAP3K11BRD4 | |
| SCHEMBL25196025 | 0.86 | MAPK8 (0.36) | DYRK1ACLK2CLK3MAP3K11BRD4 | |
| SCHEMBL30347848 | 0.85 | BRD4 (0.38) | DYRK1ACLK2CLK3BRD4DYRK1B | |
| SCHEMBL25557327 | 0.85 | BRD4 (0.38) | DYRK1ACLK2CLK3BRD4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129104-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2025-04-24 | — | — | US | claimed |
| EP-4415818-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AS DYRK1A INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2024-08-21 | — | — | EP | claimed |
| WO-2023064361-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AS DYRK1A INHIBITORS | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129104-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | DYRK1A 1/4885CLK2 466/4885CLK3 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.