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SCHEMBL30349107

SCHEMBL30349107

COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(NC(=O)C(C)C)nc43)[C@](C)(F)[C@@H]2OP(OCCC#N)[Au](C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.40
▸ TYMP P19971 6/20 0.40
▸ TAS1R3 Q7RTX0 1/20 0.31
▸ TAS1R1 Q7RTX1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31657632 0.91 TYMP (0.40) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL30091735 0.91 TYMP (0.40) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL30396329 0.80 TYMP (0.51) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL23425410 0.80 KDM4E (0.46) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL25307592 0.80 TYMP (0.45) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL24166806 0.80 TYMP (0.45) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL22401412 0.80 TYMP (0.45) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL23456230 0.80 TYMP (0.45) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL1598576 0.80 TYMP (0.45) KDM4ETYMPTAS1R3TAS1R1
SCHEMBL7197818 0.79 KDM4E (0.48) KDM4ETYMPTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4419536-A1 OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES Alnylam Pharmaceuticals, Inc. (US) 2024-08-28 — — EP disclosed
WO-2023069495-A1 OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2023-04-27 — — WO disclosed
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