SCHEMBL30350102

SCHEMBL30350102

O=C(O)CCc1ccc2cc(-c3ccccc3Oc3ccccc3)ccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 10/20 1.00
FFAR1 O14842 10/20 0.55
SRD5A2 P31213 1/20 0.49
CYP1A2 P05177 1/20 0.49
PTGER1 P34995 1/20 0.46
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17882567 1.00 FFAR4 (1.00) FFAR4FFAR1SRD5A2CYP1A2PTGER1
SCHEMBL3882947 0.89 FFAR4 (0.80) FFAR4FFAR1SRD5A2CYP1A2
SCHEMBL17882570 0.88 FFAR4 (1.00) FFAR4FFAR1CYP1A2PTGER1PTGER4
SCHEMBL30349972 0.88 FFAR4 (1.00) FFAR4FFAR1CYP1A2PTGER1PTGER4
SCHEMBL3992963 0.88 FFAR4 (0.78) FFAR4FFAR1SRD5A2
SCHEMBL30350124 0.82 FFAR4 (0.69) FFAR4FFAR1SRD5A2CYP1A2
SCHEMBL17882757 0.82 FFAR4 (0.69) FFAR4FFAR1SRD5A2CYP1A2
SCHEMBL29013543 0.82 FFAR4 (0.70) FFAR4FFAR1
SCHEMBL17882942 0.82 FFAR4 (0.73) FFAR4FFAR1SRD5A2CYP1A2PTGER3
SCHEMBL30350166 0.82 FFAR4 (0.73) FFAR4FFAR1SRD5A2CYP1A2PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107567443-B Biaryl derivatives as GPR120 agonists 株式会社LG化学 2023-04-28 CN claimed
CN-107567443-B Biaryl derivatives as GPR120 agonists 株式会社LG化学 2023-04-28 CN disclosed
CN-115925679-A Biaryl derivatives as GPR120 agonists 株式会社LG化学 2023-04-07 CN disclosed