Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 6/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19510658 | 1.00 | AOC3 (0.60) | AOC3HRH3KCNH2CASP3ITGB3 | |
| SCHEMBL1500259 | 0.88 | AOC3 (0.47) | AOC3CASP3ITGB3PRMT5WDR77 | |
| SCHEMBL22713778 | 0.86 | AOC3 (0.61) | AOC3HRH3KCNH2ITGB3ITGA2B | |
| SCHEMBL22713735 | 0.85 | AOC3 (0.69) | AOC3ITGB3ITGA2BPRMT5WDR77 | |
| SCHEMBL15690244 | 0.82 | AOC3 (0.56) | AOC3MAPT | |
| SCHEMBL2178732 | 0.81 | HDAC6 (0.46) | AOC3CASP3PRMT5WDR77 | |
| SCHEMBL1817669 | 0.80 | GRM5 (0.61) | HRH3KCNH2PRMT5WDR77GRM5 | |
| SCHEMBL18766026 | 0.80 | KDM4E (0.46) | AOC3CASP3ITGB3ITGA2B | |
| SCHEMBL19511001 | 0.78 | AOC3 (0.53) | AOC3HRH3KCNH2ITGB3ITGA2B | |
| SCHEMBL30345542 | 0.78 | AOC3 (0.53) | AOC3HRH3KCNH2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| CN-115925679-A | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-07 | — | — | CN | disclosed |