Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.31 |
| ▸ | RELA | Q04206 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554167 | 1.00 | NSD2 (0.33) | NSD2CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL25554404 | 0.93 | NSD2 (0.38) | NSD2CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL30353064 | 0.93 | NSD2 (0.38) | NSD2CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL30353048 | 0.89 | CYP19A1 (0.34) | NSD2CYP19A1CYP11B1CYP11B2ALOX5AP | |
| SCHEMBL25057820 | 0.89 | NSD2 (0.34) | NSD2CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL23949272 | 0.89 | CYP19A1 (0.34) | NSD2CYP19A1CYP11B1CYP11B2ALOX5AP | |
| SCHEMBL30256634 | 0.89 | NSD2 (0.34) | NSD2CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL25058224 | 0.89 | NSD2 (0.34) | NSD2CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL30257266 | 0.89 | NSD2 (0.34) | NSD2CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL25555475 | 0.89 | CYP11B1 (0.34) | NSD2CYP19A1CYP11B1CYP11B2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |