Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25057937 | 1.00 | GRM5 (0.37) | GRM5FFAR1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25554262 | 0.93 | GRM5 (0.36) | GRM5FFAR1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30353098 | 0.93 | GRM5 (0.36) | GRM5FFAR1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25555428 | 0.90 | CYP19A1 (0.35) | GRM5CYP19A1CYP11B1CYP11B2NSD2 | |
| SCHEMBL30353389 | 0.90 | CYP11B1 (0.36) | CYP19A1CYP11B1CYP11B2NSD2 | |
| SCHEMBL30353118 | 0.90 | GRM5 (0.37) | GRM5CYP19A1CYP11B1CYP11B2NSD2 | |
| SCHEMBL25058666 | 0.90 | CYP11B1 (0.36) | CYP19A1CYP11B1CYP11B2NSD2 | |
| SCHEMBL30256984 | 0.90 | NSD2 (0.34) | CYP19A1CYP11B1CYP11B2NSD2 | |
| SCHEMBL25554968 | 0.90 | NSD2 (0.34) | CYP19A1CYP11B1CYP11B2NSD2 | |
| SCHEMBL25554896 | 0.90 | GRM5 (0.37) | GRM5CYP19A1CYP11B1CYP11B2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |