Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554479 | 1.00 | GRM5 (0.39) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL25554247 | 0.92 | CYP11B1 (0.41) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL25554119 | 0.92 | GRM5 (0.38) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL30353104 | 0.92 | GRM5 (0.38) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL30256876 | 0.90 | TAAR1 (0.42) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL25554091 | 0.90 | TAAR1 (0.42) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL25554092 | 0.87 | GRM5 (0.41) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL30257088 | 0.87 | GRM5 (0.41) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL25251491 | 0.87 | GRM5 (0.38) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 | |
| SCHEMBL30257430 | 0.87 | GRM5 (0.38) | GRM5CYP11B1CYP11B2CYP19A1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |