Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 3/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554412 | 1.00 | CYP19A1 (0.33) | CYP19A1CYP11B1CYP11B2SCN9ANTRK1 | |
| SCHEMBL25418964 | 0.93 | KMT2A (0.38) | CYP19A1CYP11B1CYP11B2SCN9ANSD2 | |
| SCHEMBL30353123 | 0.93 | KMT2A (0.38) | CYP19A1CYP11B1CYP11B2SCN9ANSD2 | |
| SCHEMBL25568231 | 0.92 | NSD2 (0.36) | CYP19A1CYP11B1CYP11B2SCN9ANTRK1 | |
| SCHEMBL25554428 | 0.91 | CYP19A1 (0.32) | CYP19A1CYP11B1CYP11B2SCN9ANSD2 | |
| SCHEMBL30257270 | 0.87 | CYP19A1 (0.35) | CYP19A1CYP11B1CYP11B2SCN9ANSD2 | |
| SCHEMBL25057903 | 0.87 | CYP19A1 (0.35) | CYP19A1CYP11B1CYP11B2SCN9ANSD2 | |
| SCHEMBL30257224 | 0.86 | CYP19A1 (0.34) | CYP19A1CYP11B1CYP11B2SCN9ANSD2 | |
| SCHEMBL23949272 | 0.86 | CYP19A1 (0.34) | CYP19A1CYP11B1CYP11B2SCN9ANSD2 | |
| SCHEMBL30353048 | 0.86 | CYP19A1 (0.34) | CYP19A1CYP11B1CYP11B2SCN9ANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |