Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | NSD2 | O96028 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554168 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL30257119 | 0.94 | KDM1A (0.35) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL25554269 | 0.94 | KDM1A (0.35) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL30257237 | 0.94 | NSD2 (0.37) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL25554402 | 0.94 | NSD2 (0.37) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL25058417 | 0.90 | KDM1A (0.33) | KDM1ACYP19A1NSD2CYP11B1CYP11B2 | |
| SCHEMBL30353103 | 0.90 | KDM1A (0.33) | KDM1ACYP19A1NSD2CYP11B1CYP11B2 | |
| SCHEMBL25057820 | 0.89 | NSD2 (0.34) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL30257266 | 0.89 | NSD2 (0.34) | SMN1; SMN2NPC1RAB9ATP53NFKB1 | |
| SCHEMBL25058224 | 0.89 | NSD2 (0.34) | SMN1; SMN2NPC1RAB9ATP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |