Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.90 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.90 |
| ▸ | ERN1 | O75460 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | CCND1 | P24385 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicyladehyde SCHEMBL11675350 | 0.98 | TRIM24 (0.86) | TRIM24TRIM33ERN1LMNAMEN1 | |
| Salicyladehyde SCHEMBL28495392 | 0.98 | TRIM24 (0.86) | TRIM24TRIM33ERN1LMNAMEN1 | |
| Salicyladehyde SCHEMBL28758497 | 0.95 | TRIM24 (0.90) | TRIM24TRIM33ERN1LMNAMEN1 | |
| Salicyladehyde SCHEMBL29386538 | 0.95 | — | — | |
| Salicyladehyde SCHEMBL901265 | 0.95 | TRIM24 (1.00) | TRIM24TRIM33ERN1LMNAMEN1 | |
| Salicyladehyde SCHEMBL15395 | 0.95 | — | — | |
| Salicyladehyde SCHEMBL27791581 | 0.93 | TRIM24 (0.86) | TRIM24TRIM33ERN1LMNAMEN1 | |
| Salicyladehyde SCHEMBL23628380 | 0.92 | TRIM24 (0.95) | TRIM24TRIM33ERN1LMNAMEN1 | |
| Salicyladehyde SCHEMBL8343246 | 0.92 | TRIM24 (0.95) | TRIM24TRIM33ERN1LMNAMEN1 | |
| Salicyladehyde SCHEMBL4456334 | 0.92 | TRIM24 (0.95) | TRIM24TRIM33ERN1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416174-B | Piperazine ring-containing salicylaldehyde hydrazine compound and preparation and application thereof | 华南理工大学 | 2022-08-16 | — | — | CN | claimed |
| CN-111875519-B | Salicylaldehyde hydrazine AIE compound, preparation method thereof and application of salicylaldehyde hydrazine AIE compound in constructing xerogel sensing film with high luminous efficiency | 华南理工大学 | 2021-10-26 | — | — | CN | claimed |
| CN-113416174-A | Piperazine ring-containing salicylaldehyde hydrazine compound and preparation and application thereof | 华南理工大学 | 2021-09-21 | — | — | CN | claimed |
| CN-111875519-A | Salicylaldehyde hydrazine AIE compound, preparation method thereof and application of salicylaldehyde hydrazine AIE compound in constructing xerogel sensing film with high luminous efficiency | 华南理工大学 | 2020-11-03 | — | — | CN | claimed |
| CN-114621214-B | Antibacterial Schiff base N-acylate, and preparation method and application thereof | 宜春学院 | 2024-04-26 | — | — | CN | disclosed |
| CN-113416174-B | Piperazine ring-containing salicylaldehyde hydrazine compound and preparation and application thereof | 华南理工大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-113416174-B | Piperazine ring-containing salicylaldehyde hydrazine compound and preparation and application thereof | 华南理工大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-113416174-B | Piperazine ring-containing salicylaldehyde hydrazine compound and preparation and application thereof | 华南理工大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114621214-A | Antibacterial Schiff base N-acylate and preparation method and application thereof | 宜春学院 | 2022-06-14 | — | — | CN | disclosed |
| CN-111875519-B | Salicylaldehyde hydrazine AIE compound, preparation method thereof and application of salicylaldehyde hydrazine AIE compound in constructing xerogel sensing film with high luminous efficiency | 华南理工大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-111875519-B | Salicylaldehyde hydrazine AIE compound, preparation method thereof and application of salicylaldehyde hydrazine AIE compound in constructing xerogel sensing film with high luminous efficiency | 华南理工大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-111875519-B | Salicylaldehyde hydrazine AIE compound, preparation method thereof and application of salicylaldehyde hydrazine AIE compound in constructing xerogel sensing film with high luminous efficiency | 华南理工大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-113416174-A | Piperazine ring-containing salicylaldehyde hydrazine compound and preparation and application thereof | 华南理工大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-111875519-A | Salicylaldehyde hydrazine AIE compound, preparation method thereof and application of salicylaldehyde hydrazine AIE compound in constructing xerogel sensing film with high luminous efficiency | 华南理工大学 | 2020-11-03 | — | — | CN | disclosed |
| CN-111875519-A | Salicylaldehyde hydrazine AIE compound, preparation method thereof and application of salicylaldehyde hydrazine AIE compound in constructing xerogel sensing film with high luminous efficiency | 华南理工大学 | 2020-11-03 | — | — | CN | disclosed |
| CN-111875519-A | Salicylaldehyde hydrazine AIE compound, preparation method thereof and application of salicylaldehyde hydrazine AIE compound in constructing xerogel sensing film with high luminous efficiency | 华南理工大学 | 2020-11-03 | — | — | CN | disclosed |
| US-8093238-B2 | Fused thiazole derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2012-01-10 | — | — | US | disclosed |
| US-20100069361-A1 | Fused Thiazole Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2010-03-18 | — | — | US | disclosed |
| EP-2076512-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008044022-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069361-A1 | Fused Thiazole Derivatives as Kinase Inhibitors | JAK1, MTOR, MOK | TRIM24 515/4885TRIM33 2721/4885ERN1 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.