Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25617474 | 1.00 | PIK3CA (0.51) | PIK3CAPIK3R1CTSLKDM4E | |
| SCHEMBL25403731 | 0.91 | PIK3CA (0.51) | PIK3CAPIK3R1CTSLKDM4E | |
| SCHEMBL30503108 | 0.91 | PIK3CA (0.51) | PIK3CAPIK3R1CTSLKDM4E | |
| SCHEMBL25617735 | 0.88 | PIK3CA (0.63) | PIK3CAPIK3R1 | |
| SCHEMBL31547941 | 0.88 | PIK3CA (0.63) | PIK3CAPIK3R1 | |
| SCHEMBL25617472 | 0.88 | PIK3CA (0.54) | PIK3CAPIK3R1 | |
| SCHEMBL30353544 | 0.88 | PIK3CA (0.54) | PIK3CAPIK3R1 | |
| SCHEMBL31547982 | 0.87 | PIK3CA (0.57) | PIK3CAPIK3R1 | |
| SCHEMBL24099574 | 0.87 | PIK3CA (0.57) | PIK3CAPIK3R1 | |
| SCHEMBL30503112 | 0.78 | PIK3CA (0.57) | PIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118946360-A | Bicyclic heteroarenes and methods of use thereof | 奇尼塔公司 | 2024-11-12 | — | — | CN | disclosed |
| EP-4444317-A2 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107623-A2 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-4161523-A1 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Yumanity Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |