Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 1.00 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421472 | 1.00 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL31139111 | 1.00 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL30184827 | 1.00 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24940753 | 1.00 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24939959 | 1.00 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24939963 | 1.00 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24940672 | 1.00 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL25586304 | 0.96 | MC4R (0.92) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24940872 | 0.96 | MC4R (0.92) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24940690 | 0.92 | MC4R (0.85) | MC4RMC5RMC3RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161927-A1 | SPIRO COMPOUNDS AS MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | Pfizer Inc. (US) | 2023-04-12 | — | — | EP | disclosed |