SCHEMBL30355802

SCHEMBL30355802

O=C(Nc1cc(-c2ccc(NS(=O)(=O)N3CCOCC3)c(F)c2)c2cc[nH]c2n1)C1CC1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
JAK1 P23458 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20918196 1.00 JAK1 (0.66) JAK1
SCHEMBL30355876 0.93 JAK1 (0.71) JAK1
SCHEMBL20917934 0.93 JAK1 (0.71) JAK1
SCHEMBL20918689 0.92 JAK1 (0.72) JAK1
SCHEMBL30355943 0.92 JAK1 (0.72) JAK1
SCHEMBL20917848 0.87 JAK1 (0.78) JAK1
SCHEMBL30355803 0.87 JAK1 (0.78) JAK1
SCHEMBL20918738 0.85 JAK1 (0.73) JAK1
SCHEMBL30356267 0.85 JAK1 (0.73) JAK1
SCHEMBL20918719 0.85 JAK1 (0.85) JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111372931-B Heterocyclic compounds as protein kinase inhibitors 怡诺安有限公司 2023-03-24 CN disclosed