Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917996 | 1.00 | JAK1 (0.75) | JAK1 | |
| SCHEMBL20918692 | 0.87 | JAK1 (0.76) | JAK1 | |
| SCHEMBL20918015 | 0.86 | JAK1 (0.71) | JAK1 | |
| SCHEMBL30356056 | 0.86 | JAK1 (0.71) | JAK1 | |
| SCHEMBL20930544 | 0.86 | JAK1 (1.00) | JAK1 | |
| SCHEMBL20930234 | 0.84 | JAK1 (0.54) | JAK1 | |
| SCHEMBL30356216 | 0.77 | JAK1 (0.74) | JAK1 | |
| SCHEMBL20918119 | 0.77 | JAK1 (0.74) | JAK1 | |
| SCHEMBL30009783 | 0.76 | KIT (0.47) | JAK1 | |
| SCHEMBL20917871 | 0.76 | JAK1 (0.60) | JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372931-B | Heterocyclic compounds as protein kinase inhibitors | 怡诺安有限公司 | 2023-03-24 | — | — | CN | disclosed |