Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634181 | 0.93 | SLC6A2 (0.47) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL5190981 | 0.89 | CYP3A4 (0.64) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL4669314 | 0.89 | CYP3A4 (0.64) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL3336564 | 0.89 | SCN1A (0.57) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL9242920 | 0.84 | CYP3A4 (0.59) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL10577158 | 0.83 | IDO1 (0.58) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4443321 | 0.81 | CYP3A4 (0.58) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL4667552 | 0.80 | IDO1 (0.54) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL6976130 | 0.77 | SLC6A2 (0.53) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 | |
| SCHEMBL8291381 | 0.77 | CYP3A4 (0.49) | CHRM2ADRA2ACHRM1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023047107-A1 | ARYL OR HETEROARYL DERIVED COMPOUNDS FOR THE TREATMENTS OF MICROBIAL INFECTIONS | THE UNIVERSITY OF DURHAM (GB) | 2023-03-30 | — | — | WO | disclosed |