SCHEMBL30356347

SCHEMBL30356347

CCN(C(=O)OC)N(CC)C(=O)c1cc(Br)cc(Br)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.39
LMNA P02545 2/20 0.33
MALT1 Q9UDY8 7/20 0.32
LRRK2 Q5S007 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
GFER P55789 1/20 0.30
RBP4 P02753 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL797554 1.00 DHODH (0.39) DHODHLMNAMALT1LRRK2NPC1
SCHEMBL13490109 0.95 DHODH (0.36) DHODHLMNA
SCHEMBL326444 0.95 DHODH (0.38) DHODHLMNAMALT1LRRK2
SCHEMBL31628519 0.95 DHODH (0.38) DHODHLMNAMALT1LRRK2
SCHEMBL13489592 0.94 DHODH (0.36) DHODH
SCHEMBL13489590 0.93 DHODH (0.36) DHODHLMNA
SCHEMBL14844944 0.93 DHODH (0.37) DHODHLMNALRRK2GFERMEN1
SCHEMBL13490106 0.93 DHODH (0.38) DHODHLMNA
SCHEMBL20211134 0.92 DHODH (0.38) DHODHLMNALRRK2GFERMEN1
SCHEMBL20211135 0.91 DHODH (0.39) DHODHLMNALRRK2GFERMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136787-A Pyrazole-substituted aryl sulfide compound and application thereof 青岛清原化合物有限公司 2025-06-13 CN disclosed
EP-3556211-B1 ORGANIC AMMONIUM SALTS OF ANIONIC PESTICIDES CLARIANT INT LTD (CH) 2023-01-25 EP disclosed