Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.65 |
| ▸ | MTOR | P42345 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308471 | 1.00 | CYP1A2 (0.65) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7320393 | 0.95 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7309693 | 0.94 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7314717 | 0.94 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7315686 | 0.94 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7313806 | 0.94 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7315785 | 0.94 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7313255 | 0.93 | CACNA1C (0.59) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7309578 | 0.93 | CACNA1C (0.63) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL7320497 | 0.93 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485881-B1 | PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI-INFLAMMATORY AGENTS | HARVARD COLLEGE (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20230165812-A1 | NOCICEPTOR NEURONS CONTROL CANCER IMMUNOSURVEILLANCE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165812-A1 | NOCICEPTOR NEURONS CONTROL CANCER IMMUNOSURVEILLANCE | OPRL1, MRGPRX1, RAMP1 | CYP1A2 4454/4885CYP3A4 4368/4885CYP2C9 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.