Benzo[Def]Chrysene

Benzo[Def]Chrysene

SCHEMBL30358490

c1ccc2c(c1)cc1ccc3cccc4ccc2c1c34

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 1.00
ERBB2 P04626 1/20 1.00
FYN P06241 1/20 1.00
MAOA P21397 1/20 1.00
ACHE P22303 1/20 1.00
AHR P35869 1/20 1.00
ALDH1A1 P00352 7/20 0.65
HSD17B10 Q99714 7/20 0.65
HPGD P15428 5/20 0.65
THRB P10828 1/20 0.65
CYP1B1 Q16678 3/20 0.52
HIF1A Q16665 2/20 0.52
TSHR P16473 4/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
MAPK1 P28482 1/20 0.52
CASP1 P29466 1/20 0.52
HPRT1 P00492 3/20 0.50
CYP3A4 P08684 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP1A1 P04798 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[Def]Chrysene SCHEMBL17114373 1.00 CYP1A2 (1.00) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL29352452 1.00 CYP1A2 (1.00) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL24019 1.00 CYP1A2 (1.00) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL29826740 1.00 CYP1A2 (1.00) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL29407951 1.00 CYP1A2 (1.00) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL23414475 1.00 CYP1A2 (1.00) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL11393448 0.98 CYP1A2 (0.96) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4852478 0.98 CYP1A2 (0.96) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL5473588 0.98 CYP1A2 (0.96) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL28698813 0.98 CYP1A2 (0.96) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535013-A Method for treating sewage containing polycyclic aromatic hydrocarbon by white rot fungi 山东瑞地环评科技有限公司 2023-08-04 CN claimed
CN-112028709-B Application of active silicon material in preparation of water-retention slow-release microbial fertilizer 内蒙古工业大学 2023-04-14 CN disclosed