Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 20/20 | 0.88 |
| ▸ | KCNK9 | Q9NPC2 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bafrekalant SCHEMBL21826404 | 0.94 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29457988 | 0.93 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL24208191 | 0.93 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL21904750 | 0.90 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL30359150 | 0.89 | KCNK3 (0.87) | KCNK3KCNK9 | |
| SCHEMBL30359157 | 0.87 | KCNK3 (0.88) | KCNK3KCNK9 | |
| SCHEMBL21827098 | 0.87 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL24208146 | 0.86 | KCNK3 (0.86) | KCNK3KCNK9 | |
| SCHEMBL21826296 | 0.86 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL21826463 | 0.86 | KCNK3 (1.00) | KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |