Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23805211 | 0.84 | HTR2A (0.71) | HTR2ATRPM8LTA4HPLA2G2AMAPT | |
| Hydrochloric Acid SCHEMBL274592 | 0.83 | HTR2A (0.70) | HTR2ATRPM8LTA4HPLA2G2AMAPT | |
| SCHEMBL11263785 | 0.81 | HTR2A (0.67) | HTR2ATRPM8LTA4HPLA2G2AMAPT | |
| SCHEMBL31295159 | 0.79 | HTR2A (0.71) | HTR2ATRPM8LTA4HPLA2G2AMAPT | |
| SCHEMBL31295123 | 0.79 | HTR2A (0.71) | HTR2ATRPM8LTA4HPLA2G2AMAPT | |
| SCHEMBL23805285 | 0.79 | HTR2A (0.60) | HTR2ATRPM8LTA4HPLA2G2AMAPT | |
| SCHEMBL23805245 | 0.77 | HTR2A (0.72) | HTR2ATRPM8LTA4HPLA2G2AMAPT | |
| SCHEMBL6615000 | 0.77 | HTR2A (0.68) | HTR2ATRPM8LTA4HPLA2G2AMTNR1A | |
| SCHEMBL30249165 | 0.77 | HTR2A (0.67) | HTR2ATRPM8LTA4HPLA2G2AMAPT | |
| SCHEMBL23805297 | 0.76 | HTR2A (0.67) | HTR2ATRPM8LTA4HPLA2G2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140635-A1 | 3-(2-(Aminoethyl)-Indol-4-ol Derivatives, Methods of Preparation Thereof, and the Use as 5-HT2 Receptor Modulators | BRIGHT MINDS BIOSCIENCES INC. (CA) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140635-A1 | 3-(2-(Aminoethyl)-Indol-4-ol Derivatives, Methods of Preparation Thereof, and the Use as 5-HT2 Receptor Modulators | HTR2C, HTR2A, HTR2B | HTR2A 2/4885TRPM8 379/4885LTA4H 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.