SCHEMBL30359264

SCHEMBL30359264

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.61
NPY1R P25929 6/20 0.61
NPY2R P49146 4/20 0.61
NPY5R Q15761 4/20 0.61
MMP2 P08253 1/20 0.54
GNPAT O15228 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630650 1.00 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30375565 1.00 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30845381 0.99 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30958098 0.99 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30958097 0.99 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL29406322 0.99 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30565144 0.97 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RMMP2
SCHEMBL30118077 0.96 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RGNPAT
SCHEMBL29549393 0.96 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RGNPAT
SCHEMBL29406427 0.96 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RGNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250327817-A1 DETECTION OF PREDICTORS OF PREECLAMPSIA UNIV IOWA RES FOUND (US) 2025-10-23 US disclosed
EP-3237435-B1 METABOLICALLY STABLE APELIN ANALOGS IN THE TREATMENT OF DISEASE MEDIATED BY THE APELIN RECEPTOR INST NAT SANTE RECH MED (FR) 2023-05-24 EP disclosed